Neonatal Nurse Practitioner Practice Exam

When giving an IM injection to a neonate weighing less than 1500 gm, what is the maximum volume that should be injected per thigh?

1. 0.3 ml

2. 0.5 ml

3. 1.0 ml

4. 1.5 ml

The correct answer is: 0.5 ml

In neonates weighing less than 1500 grams, it is essential to consider their smaller muscle mass and less developed adipose tissue when administering intramuscular (IM) injections. The recommended maximum volume for an IM injection in a neonate of this weight is typically 0.5 ml per thigh. This limit helps to minimize the risk of complications such as pain, muscle damage, or abscess formation that could arise from injecting a larger volume than the muscle can handle. By adhering to the guideline of 0.5 ml, the healthcare provider ensures that the injection is both effective and safe. This approach reflects current best practices focusing on the delicate nature of neonates and the importance of administering medications in a manner that reduces the risk of adverse effects. Therefore, selecting 0.5 ml as the maximum volume for an IM injection in this population supports optimal patient care and aligns with established neonatal pharmacology principles.